Disrupted functional connectivity of the periaqueductal gray in chronic low back pain

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Disrupted functional connectivity of the periaqueductal gray in chronic low back pain

Chronic low back pain is a common neurological disorder. The periaqueductal gray (PAG) plays a key role in the descending modulation of pain. In this study, we investigated brain resting state PAG functional connectivity (FC) differences between patients with chronic low back pain (cLBP) in low pain or high pain condition and matched healthy controls (HCs). PAG seed based functional connectivit...

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PERIAQUEDUCTAL GRAY 1 Running head: PERIAQUEDUCTAL GRAY Common representation of pain and negative emotion in the midbrain periaqueductal gray

Human neuroimaging offers a powerful way to connect animal and human research on emotion, with profound implications for psychological science. However, the gulf between animal and human studies remains a formidable obstacle: Human studies typically focus on the cortex and a few subcortical regions such as the amygdala, whereas deeper structures such as the brainstem periaqueductal gray (PAG) p...

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A comparative study of trunk proprioception between patients with chronic non-specific low back pain and discopathic low back pain

Introduction: Low back pain is one of the most common disorders in modern society. Disturbed properioception can be a possible cause of low back pain and can cause recurrence of low back pain. Previous studies have shown that low back pain reduces proprioception due to instability in the low back. Since the degenerative process of disc herniation is one of the important factors in exacerbating ...

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The Effects of Consecutive Supervised Functional Lumbar Stabilizing Exercises on the Postural Balance and Functional Disability in Low Back Pain

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 Aims and background: Chronic low back pain (LBP) is one of the most common and costly musculoskeletal disorders in societies that have been suggested for many therapies. Exercise therapy is one of the most widely used methods in control and treatment of chronic low back pain. The purpose of the present study is to systematically review English-language studies that have investigated the effect...

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ژورنال

عنوان ژورنال: NeuroImage: Clinical

سال: 2014

ISSN: 2213-1582

DOI: 10.1016/j.nicl.2014.08.019